USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q8WUM4 USC-OGP 2-DE database:  Q8WUM4 Q8WUM4 General information about the entry View entry in simple text format Entry name PDC6I_HUMAN Primary accession number Q8WUM4 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Programmed cell death 6-interacting protein; Short=PDCD6-interacting protein; AltName: Full=ALG-2-interacting protein 1; AltName: Full=ALG-2-interacting protein X; AltName: Full=Hp95;. Gene name Name=PDCD6IP Synonyms=AIP1, ALIX, KIAA1375 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1107: pI=6.36; Mw=111581 Cross-references UniProtKB/Swiss-Prot Q8WUM4; PDC6I_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PDC6I_HUMAN Primary accession number Q8WUM4 Secondary accession number(s) C5MQH7 E9PFU1 Q6NUS1 Q9BX86 Q9NUN0 Q9P2H2 Q9UKL5 Sequence was last modified on  March 1, 2002 (version 1) Annotations were last modified on  March 15, 2017 (version 160) Name and origin of the protein Description RecName: Full=Programmed cell death 6-interacting protein; Short=PDCD6-interacting protein; AltName: Full=ALG-2-interacting protein 1; AltName: Full=ALG-2-interacting protein X; AltName: Full=Hp95; Gene name Name=PDCD6IP Synonyms=AIP1, ALIX, KIAA1375 Encoded on Name=PDCD6IP; Synonyms=AIP1, ALIX, KIAA1375 Keywords 3D-structure; Acetylation; Alternative splicing; Apoptosis; Cell cycle; Cell division; Cell junction; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Host-virus interaction; Methylation; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Secreted; Tight junction; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF349951; AAK20398.1; -; mRNA EMBL GQ131806; ACS12984.1; -; mRNA EMBL AF151793; AAF08220.1; -; mRNA EMBL BT007367; AAP36031.1; -; mRNA EMBL AC112220; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC123901; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC020066; AAH20066.1; -; mRNA EMBL BC068454; AAH68454.1; -; mRNA EMBL AK002122; BAA92092.1; ALT_INIT; mRNA EMBL AB037796; BAA92613.1; -; mRNA CCDS CCDS2660.1; -. [Q8WUM4-1]; . CCDS CCDS54561.1; -. [Q8WUM4-2]; . RefSeq NP_001155901.1; NM_001162429.2. [Q8WUM4-2]; . RefSeq NP_001243121.1; NM_001256192.1. [Q8WUM4-3]; . RefSeq NP_037506.2; NM_013374.5. [Q8WUM4-1]; . UniGene Hs.475896; -; . PDB 2OEV; X-ray; 3.30 A; A=1-698 PDB 2OEW; X-ray; 2.55 A; A=1-359 PDB 2OEX; X-ray; 2.58 A; A/B=360-702 PDB 2OJQ; X-ray; 2.87 A; A=360-702 PDB 2R02; X-ray; 2.60 A; A=2-698 PDB 2R03; X-ray; 2.59 A; A=2-698 PDB 2R05; X-ray; 2.55 A; A=2-698 PDB 2XS1; X-ray; 2.30 A; A=1-698 PDB 2XS8; X-ray; 2.50 A; A=1-698 PDB 2ZNE; X-ray; 2.20 A; C/D=799-812 PDB 3C3O; X-ray; 2.15 A; A=1-359 PDB 3C3Q; X-ray; 2.10 A; A=1-359 PDB 3C3R; X-ray; 2.02 A; A=1-359 PDB 3E1R; X-ray; 2.00 A; C=797-809 PDB 3WUV; X-ray; 2.79 A; C/F/I/L/O/R=796-810 PDB 4JJY; X-ray; 6.50 A; A/B=355-708 PDBsum 2OEV; -; . PDBsum 2OEW; -; . PDBsum 2OEX; -; . PDBsum 2OJQ; -; . PDBsum 2R02; -; . PDBsum 2R03; -; . PDBsum 2R05; -; . PDBsum 2XS1; -; . PDBsum 2XS8; -; . PDBsum 2ZNE; -; . PDBsum 3C3O; -; . PDBsum 3C3Q; -; . PDBsum 3C3R; -; . PDBsum 3E1R; -; . PDBsum 3WUV; -; . PDBsum 4JJY; -; . ProteinModelPortal Q8WUM4; -; . SMR Q8WUM4; -; . BioGrid 115332; 111; . DIP DIP-29327N; -; . IntAct Q8WUM4; 55; . MINT MINT-4999333; -; . STRING 9606.ENSP00000411825; -; . iPTMnet Q8WUM4; -; . PhosphoSitePlus Q8WUM4; -; . SwissPalm Q8WUM4; -; . BioMuta PDCD6IP; -; . DMDM 31076831; -; . UCD-2DPAGE Q8WUM4; -; . EPD Q8WUM4; -; . MaxQB Q8WUM4; -; . PaxDb Q8WUM4; -; . PeptideAtlas Q8WUM4; -; . PRIDE Q8WUM4; -; . DNASU 10015; -; . Ensembl ENST00000307296; ENSP00000307387; ENSG00000170248. [Q8WUM4-1]; . Ensembl ENST00000457054; ENSP00000411825; ENSG00000170248. [Q8WUM4-2]; . GeneID 10015; -; . KEGG hsa:10015; -; . UCSC uc003cfx.5; human. [Q8WUM4-1]; . CTD 10015; -; . DisGeNET 10015; -; . GeneCards PDCD6IP; -; . H-InvDB HIX0163463; -; . HGNC HGNC:8766; PDCD6IP; . HPA CAB016212; -; . HPA HPA011905; -; . MIM 608074; gene; . neXtProt NX_Q8WUM4; -; . OpenTargets ENSG00000170248; -; . PharmGKB PA33116; -; . eggNOG KOG2220; Eukaryota; . eggNOG ENOG410XQX6; LUCA; . GeneTree ENSGT00780000121909; -; . HOGENOM HOG000006938; -; . HOVERGEN HBG053533; -; . InParanoid Q8WUM4; -; . KO K12200; -; . OMA QVKECYQ; -; . OrthoDB EOG091G04NC; -; . PhylomeDB Q8WUM4; -; . TreeFam TF323502; -; . Reactome R-HSA-162588; Budding and maturation of HIV virion; . Reactome R-HSA-5210891; Uptake and function of anthrax toxins; . ChiTaRS PDCD6IP; human; . EvolutionaryTrace Q8WUM4; -; . GeneWiki PDCD6IP; -; . GenomeRNAi 10015; -; . PRO PR:Q8WUM4; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000170248; -; . CleanEx HS_PDCD6IP; -; . ExpressionAtlas Q8WUM4; baseline and differential; . Genevisible Q8WUM4; HS; . GO GO:0042641; C:actomyosin; ISS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070971; C:endoplasmic reticulum exit site; IMP:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:1903561; C:extracellular vesicle; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0001772; C:immunological synapse; IDA:BHF-UCL; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IPI:UniProtKB; . GO GO:0031871; F:proteinase activated receptor binding; IPI:UniProtKB; . GO GO:0000915; P:actomyosin contractile ring assembly; ISS:UniProtKB; . GO GO:0006915; P:apoptotic process; IEA:UniProtKB-KW; . GO GO:0070830; P:bicellular tight junction assembly; ISS:UniProtKB; . GO GO:0000920; P:cell separation after cytokinesis; IMP:UniProtKB; . GO GO:0045199; P:maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB; . GO GO:0036258; P:multivesicular body assembly; NAS:ParkinsonsUK-UCL; . GO GO:1903543; P:positive regulation of exosomal secretion; IMP:UniProtKB; . GO GO:1903553; P:positive regulation of extracellular exosome assembly; IMP:UniProtKB; . GO GO:0015031; P:protein transport; IEA:UniProtKB-KW; . GO GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB; . GO GO:1903551; P:regulation of extracellular exosome assembly; IMP:UniProtKB; . GO GO:0090559; P:regulation of membrane permeability; ISS:UniProtKB; . GO GO:0090611; P:ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; IMP:UniProtKB; . GO GO:0039702; P:viral budding via host ESCRT complex; IGI:UniProtKB; . GO GO:0019058; P:viral life cycle; TAS:Reactome; . Gene3D 1.25.40.280; -; 1; . InterPro IPR025304; ALIX_V_dom; . InterPro IPR004328; BRO1_dom; . Pfam PF13949; ALIX_LYPXL_bnd; 1; . Pfam PF03097; BRO1; 1; . SMART SM01041; BRO1; 1; . PROSITE PS51180; BRO1; 1; .

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